Objectives: The purpose of the present study is to investigate monocyte to high–density lipoprotein cholesterol (HDL–C) ratio (MHR) in the male with idiopathic hypogonadotropic hypogonadism (IHH).  Methods: This study includes 31 men with IHH without previous treatment for the disease and 44 healthy men.  The blood sampling, anthropometric measures, and physical examination were undertaken by all the participants. 

Results: There was no statistically significant difference between the patients and controls in terms of the mean HDL–C, mean monocyte count, and mean MHR.  The MHR also was not correlated with the other hematological parameters and the total testosterone. Conclusion: Previous studies have shown that IHH patients with low testosterone levels lead to an impaired glucose metabolism, and an increased cardiovascular risk.  MHR also has been shown to be an indicator of cardiovascular risk in previous studies.  In this study, we could not find an increased MHR value in patients with IHH.