Background: Atherosclerotic cardiovascular diseases are the most frequent cause of mortality and morbidity around the world. This study primarily aims to observe the effect of regular practices of yoga and self–discipline on serum uric acid, creatinine, fibrinogen, HbA1C and adiponectin in coronary artery disease patients.

Method: In present study 258 patients both male and female having coronary artery disease were selected randomly from Department of Cardiology, KGMU, Lucknow. Subjects were randomly divided in to two Groups–Yoga group and Non–Yoga group,129 patients in each group. Out of these total 258 patients 208 completed the study protocol. The yogic intervention consisted of five days in a week (35–40 min/day), till six months in Physiology department KGMU, Lucknow. Biochemical testing was done of both groups before yogic intervention and again after 6 months of yogic intervention.

Result: In present study, uric acid (p<0.01), creatinine (p<0.02), fibrinogen (p<0.04) were changed significantly while Glycosylated hemoglobin (p<0.10), and adiponectin (p<0.15) levels does not change significantly.

Conclusion: Reduction of serum uric acid, creatinine, fibrinogen, HbA1C and increase in serum adiponectin level after regular practices of yoga. Therefore, yogic practices included in this study are beneficial for the patients of coronary artery disease.