IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-3-18232 Original Research Paper The clinical spectrum of Vogt-Koyanagi-Harada syndrome in a tertiary care center of kumaon region of uttarakhand Singhal Dr. Dr.Nitin Mehrotra Dr. March 2019 8 3 01 02 ABSTRACT

Aim; To report the clinical spectrum, management, and outcome in typical cases of Vogt–Koyanagi–Harada Syndrome (VKH) in a tertiary care center in kumaun region of uttarakhand. Materials and methods; It is a retrospective study of VKH patients attending OPD of department of ophthalmology G.M.C.Haldwani ,Uttarakhand. The diagnosis of VKH disease was established by “The revised Diagnostic Criteria for VKH disease established at the First international Workshop on Vogt–Koyanagi–Harada disease”. Results; 58 eyes of 30 patients (age range 24–64 years) were included. The classification of the cases with regard to VKH disease was as follows: 3 eyes were classified as complete, 20 eyes as incomplete, and 35 eyes as probable VKH disease. Commonest extraocular manifestation noted in 17 cases was headache. The more common ocular presentations were vitritis (53 eyes) and exudative retinal detachment in the posterior pole (51 eyes), disc hyeperemia(37eyes) . All patients were managed on systemic steroids, and few with systemic immunosuppressive therapy. Majority of the participants had good visual outcome. Conclusion; Early recognition and aggressive treatment of VKH disease result in good visual outcome in typical VKH cases