IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-3-18251 Original Research Paper PREVALENCE AND CLINICAL PROFILE OF PULMONARY ARTERIAL HYPERTENSION IN CASES OF POST TUBERCULAR FIBROSIS Krishnendu Bera Dr. Dr. Supriya Sarkar Dr. March 2019 8 3 01 02 ABSTRACT

Pulmonary Hypertension is a hemodynamic and pathophysiological defect found in many clinical conditions, most commonly heart and lung diseases. The pulmonary circulation normally is a high flow, low–resistance, low pressure system that carries blood to the pulmonary microcirculation where the blood takes up oxygen and unloads excess CO2. We have correlated CT fibrosis score with ECHO PASP and cardiac catheterization PASP, mPAP and PCWP to assess the presence of pulmonary hypertension and to quantify the severity of the disease. In our study, 30 patients with post tubercular fibrosis were studied in chest medicine department and cardiology department of NRSMCH. We found from our study that the patients with significant lung damage ( CTfibrosis score>10), have higher probability of having P–PULMONALE on ECG signifying pulmonary hypertension and right ventricular hypertrophy.Patients with higher CT fibrosis scores were found to have higher probability of having pulmonary hypertension as evidenced by ECHO PASP, cardiac catheterization PASP, mPAP and PCWP values. All patients who have P–PULMONALE on ECG were found to have pulmonary hypertension from ECHO PASP, cardiac catheterization PASP, mPAP, PCWP values