AIMS and OBJECTIVES: Aim is to study the prevalence of hormones receptor among the patients of carcinoma breast and its co–relation with several factor like tumour size, tumour histology, stage, grade, nodal status, menstrual status etc. and to asses the role of harmone receptor as prognostic factor at Patna Medical College & Hospital, Patna. MATERIAL AND METHODS: The study was performed among the patients attending surgery out patients department follow up clinic and all patients admitted in indoor ward with carcinoma breast during July 2011 to June 2013 all together data of 30 patients work collected. RESULTS AND CONCLUSSION: The prevalence of positive ER and PR was found in 53.33% and 43.33% respectively. In pre menopausal and post menopausal patients the figures are (33.33%, 22.22%) and (83.33%, 75%) respectively. Age of the patients ranges from 30–80 years (mean as =47.8 years) average size of tumor 4.62 cm tumors size has an inverse correlation with ER/PR positivity which is statistically significant (p<0.05%). Most of patients belong to well differentiated group. Almost all patients presented with IDC (infiltrating Duct Carcinoma). The prognostic implication of ER/PR receptors assessed by notingham prognostic index. Implies good prognosis for ER/PR positive as oppose to negative receptor status.