Introduction: Nodular goitre has become a common endocrine problem in the world today, it is defined as the presence of a palpable nodule in the otherwise normal thyroid gland. The aim of this study was to study the incidence of malignancy and other clinical parameters of solitary thyroid nodules. Incidence of malignancy was 10–20%, being more common in females with a mean age of 35 years. Methods: A prospective study was done in 83 patients with solitary thyroid swelling by taking their detailed medical history and conducting clinical examinations under the Department Of General Surgery, ASRAM Medical College, Eluru from June 2016 to May 2018 Results: Swelling in front of the neck was the most common presentation. Mean age of the incidence of solitary thyroid nodule was 35 years. Incidence of malignancy in solitary thyroid nodule was 16.86% and were frequent in females than males in the ratio of 7.3:1. Conclusions: From the results obtained and observations done we can conclude that 16.86% of solitary thyroid nodules are malignant, with female preponderance and a mean age of 35years