The purpose of this study is to assess the efficacy and outcomes of intra–arterial thrombolysis in the treatment of acute occlusions of the lower limb over a three year period. Material and Methods. We analysed 17 patients who had been treated in our department. There were acute ischemias of stage I, IIa and IIb according to the Rutherford classification. The data prior to, and after thrombolysis was analysed. We used urokinase, Alteplase,tenectaplase as a thrombolytic agent.. Results.Most patients are males The main indications for treatment were class 2 ischemia . All patients were performed outpatient follow up. Technical success rate is 88%, patency is is (64%),limb salvage (76%),ABI improvement 76%,one patient underwent femorotibialbypass surgery , no mortality seen. Conclusions. Intraarterial thrombolysis is an effective treatment method in acute limb ischemia for selected patients .long duration of symptoms multiple comorbities with smoking history increase the risk for amputation