Gilbert’s syndrome is benign,inherited condition that runs in the families,characterized by recurrent but asymptomatic episodes of mild unconjugated hyperbilirubinemia without liver pathology or haemolytic cause.This syndrome is caused due to mutation UGT1A1 gene that decreases the activity of UDP–glucuronosyl transferase1.It is mostly inherited by autosomal recessive pattern and sometimes by autosomal dominant pattern depends on type of mutation.The presence of gilberts genotype,make other pathological causes of jaundice less likely.Genetic polymorphisms in the TATA box of UDPGT gene can be identified by PCR method.We are reporting a case of 14 year old adolescent female presenting with icterus.On examination except jaundice,clinically all parameters are within normal limits.PCR revealed genetic polymorphism.