Background: In patients with acute pancreatitis 20% of the develop severe acute pancreatitis with affection of most of the organ subsequently with the adjacent fat necrosis and collection of fluid .Further they likely to develop worsening of general condition with involvement of vital organ and its failure resulting in high morbidity and mortality.Aim: To study the clinical profile of the patient with acute pancreatitis.:Study Population patients admitted in ,GovtMohanKumaramangalam Medical college,Salem, with a diagnosis of acute pancreatitis based on symptoms, lab and imaging findings were included in this study.They were evaluated for the cause, presentation and outcome and followed for a period of six months.Period: January 2017 to January 2018. Results: Male :32 female : 16 , Children:2. 20 patients with necrosis of pancreas less than 30 % I and 14 patients with 30–50% II and 16 patients necrosis more than 50% III . The severe clinical course and outcome 52.5% is seen in III group.. Multiorgan failure (MOF) was present in 4.5% of group I and 36.8%% of group II patients.72.6% in Group III. Conservative line of management was given to 74% of the study group and 82 .6% had better outcome of survival.Intervention like surgical and endoscopic therapy were given to 28.6% of the patients.. Conclusion: Patient with mild to moderate inflammation and necrosis can be managed with IV fluids and supportive care. Severe necro inflammation results in high mortality. For staging of the clinical couse and severity of the disease CT best investigation. of choice to assess the stage and severity of pancreatic necrosis