Ectodermal dysplasia(ED) is a hereditary disorders involving absence or Deficiency of tissues and structures derived from the embryonic ectoderm. Tooth agenesis is a common occurrence in patients with ED. Dental implants are an acceptable and safe rehabilitation solution in the adult patients, but usually need bone grafting as a first stage. Patient and methods: A 23–year–old male presented with anodontia and severe atrophy of the alveolar ridges associated with ectodermal dysplasia. He was treated with 3Ds bone augmentation of the maxilla and the anterior mandible. Bone blocks were harvested from the anterior iliac crest. Bilateral inferior alveolar nerve transposition of the posterior mandible were performed at this surgery. Seventeen implants were placed, eight in the maxilla and nine in the mandible. A Cement – retained full mouth implants full zirconia were fabricated 4 months after the implants placement. Results: the outcome of the treatment provided the patient oral rehabilitation with fixed prosthesis over dental implants that enhanced the patients function and esthetics. The treatment may have a great impact at the patient quality of life and the self– esteem. This patient is followed for 22 months. Conclusions: the combination of 3Ds bone augmentation, nasal floor elevation and bilateral inferior alveolar nerve transposition can give the adult patients with ectodermal dysplasia the opportunity to have full mouth rehabilitation over dental implants.