Yellow phosphorus paste with 3 % phosphorus YP, is commonly used as a Rodenticide in India. YP is a Severe local and protoplasmic toxin causing damage to gastrointestinal, hepatic, cardiovascular, and renal systems. Paste consumption symptoms are different from direct exposure to yellow phosphorus used in industries. 3% paste is often used as a suicidal drug due to its easy availability1. Fulminant hepatic failure and severe coagulopathy leads to death in untreated or late treated cases .27% mortality has been reported in phosphorus intoxication due to use firework manufacturing 3,4. The Authors present observations of symptoms, signs, investigations caused due to rodenticide containing YP and Zinc phosphide. The study also proposes diagnostic criteria based on INR ratio, platelet count and prothrombin time for early therapeutic intervention. 90 %Patients with signs of early signs of coagulopathy and deranged prothrombin time showed complete recovery from complications. Early Plasmapheresis for recovery worked best when PT INR was between 1.17–1.63. Till date only Liver transplants had been advocated as the final treatment of fulminant liver failure occurring as complication of rodenticide poisoning. The Authors concur that symptoms due to paste/powder forms of rodenticide phosphorus compounds differ from elemental phosphorus of industrial use.10 Phytomenedione and not any other form of drug is recommended. The study proposes role of a possible immune mediated autoantibody response in patients who had consumed YP/ZP. The dramatic response to plasmapheresis makes the authors propose an autoimmune/ antigenic origin in patients suffering complications due to YP/ZP without LD consumption or accidental exposure