This article is mainly to focus that is a person with high risk of cancer for people with periodontal disease. Research findings show that patients‘ risk of developing cancer may be increased by periodontal disease and tooth loss. Inflammation is a key feature in many chronic diseases such as periodontal disease,1 atheroslerosis 2but, also in cancer3. If there is an acute inflammation it is beneficial for the host by causing elimination of pathogens and it will promote wound healing. But if the problem does not resolved an the infection becomes chronic in nature then the process may even facilitate malignant transformation of cells leading to subsequent progression of cancer4. This review article intends to throw light on association between periodontal health an carcinogenesis