Dengue infection is known to elevate the liver enzymes based on the clinical presentation, infection, and is more common in patients with severe dengue. Awareness of these manifestations of hepatic involvement in dengue may be helpful in arriving at early diagnosis and avoiding morbidity and mortality. Since our hospital is tertiary care hospital, we do see a lot of children with dengue infections including those with atypical manifestations. So, an attempt has been made to study hepatic enzymes status and its prognostic significance in children with dengue virus infection.