Introduction:– Myofascial trigger points become an extreme common complaint of industrialised and corporate population who are engaged in low level static exertion as in desk jobs. A wide spectrum of symptoms are indicated, pain being the predominant one compelling individual to seek intervention. Myofascial Pain Syndrome has been shown to have negative impact on quality of life as it intervene with patient’s basic daily living activities, increasing their disability index and even effecting their utilisation of health services. Patients with trigger points present the complex clinical findings and the underlying cause has been the subject of speculation. So, this study was planned to find out the effect of myofascial release technique and soft tissue manipulation Objective:– To compare the effects of myofascial release technique soft tissue manipulation on cervical pain and cervical range of motion in patients with cervical myofascial pain syndrome. Methodology: A total of 30 patients, age 25 – 45 years, of both genders, with unilateral cervical trigger point, were selected from the Physiotherapy OPD of Punjabi University, Patiala. Patients were assessed for cervical pain and cervical range of motion with visual analogue scale (VAS) and universal goniometer respectively. After that, the patients were equally divided into two groups i.e. A & B, consisting of 15 patients in each group. Group A was treated with Myofascial Release Techniques whereas Group B was treated with Transverse Friction Massage. Both the groups were given short wave diathermy as thermotherapy. Patients were re–assessed after the completion of treatment i.e. 30 days. Results: This study shows that in both Groups i.e. Group A & Group B, there was a statistical significant difference in p–value for pain and cervical range of motion for both groups. Conclusion:– It is concluded that both the techniques i.e. myofascial release technique and transverse friction massage are equally effective in myofascial pain syndrome, indicating the improvement in the intensity of pain and cervical range of motion at the end of treatment session.