Antiphospholipid syndrome is an auto immune disorder resulting in a hypercoagulable state due to involvement of anticardiolipin , lupus anticoagulant & anti–β2 glycoprotien autoantibodies. APLA is defined by presence of thromboembolic complication & pregnancy morbidity in presence of increased titre of antiphospholipid antibodies. Antiphospholipid syndrome is classified as primary or secondary depending on its association with other auto immune disorders Primary Antiphospholipid syndrome is diagnosed in patients demonstrating the clinical & lab. criteria for disease without recognizing auto immune disease. Secondary Antiphospholipid syndrome is diagnosed in patient with other auto immune disease like SLE Management: such patients are managed with low molecular weight heparin it is started in early gestation & continue till 34 weeks