IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-4-18694 Original Research Paper Evaluation of Breast masses with Mammography and Sono-Mamography with Histopathology (FNAC/Biopsy) correlation. Peeyush Kumar Dhagat Dr. Major Narendra Yadav Dr. April 2019 8 4 01 02 ABSTRACT

Introduction: Breast cancer is the most commonly occurring female cancer in the world with an age–standardized incidence rate (ASR) of 39.0 per 100,000, which is more than twice that of the second ranked cancer (cervical cancer ASR=15.2 per 100,000). In India, carcinoma of breast is the second most common cancer (after cervical cancer) with an estimated 115,251 new diagnoses and the second most common cause of cancer–related deaths with 53,592 breast cancer deaths in 2011. In India, breast cancer accounts for 22.2% of all new cancer cases and 17.2% of all cancer deaths among women. Breast cancer in urban areas of India is three times higher than in rural regions of the country. In the past decades, great strides have been made in breast cancer screening 6 in the form of triple assessment. Given its inherent limitation and disadvantages, efforts have been made to develop several adjuvant–imaging techniques for breast cancer screening. Aim and Objectives: To evaluate the validity and accuracy of mammography and sonomammography as a tool for categorizing breast masses.If the present study justifies, then USG and mammography of breast could be included in the standard screening of the breast lump, especially in suspected cases of breast cancer. This could avoid painful interventional procedures like FNAC and core biopsy.Material and Methods:The present study was carried out at a tertiary care Hospital at New Delhi. Females more than 30 years referred to us with complaints of breast masses for mammographic and sonomammographic examination were included in the study. Patients were selected based on the inclusion and exclusion criteria. Whole–breast sonography with high resolution, 7.5 – 12 MHz, linear array transducer of GE LOGIQ P5 were performed Mammography was performed with Siemens Mammomat Novation DR Equipment in two views (i.e., cranio–caudal & medio–lateral oblique views). Finally FNAC of the lesion for cystic lesion and the histo–pathological report assessment for rest of the lesion was done. Assesment was done using BI–RADS US Assessment Category.Results: Results were corroborated using statistical analysis Conclusion:Our results indicate that breast density is important predictors of the accuracy of mammography. Breast ultrasound is more accurate than mammography in symptomatic. The accuracy of mammograms increased as women’s breasts became fattier and less dense. In women with dense breasts, ultrasound appears superior to mammography, and may be an appropriate initial imaging test in those women. However, Sono mammographic correlation is best in both.