Background: Diseases of the thyroid are manifested by alteration in hormone secretion, enlargement of the thyroid gland (goiter), or both. The principal diseases of the thyroid gland are goiter (diffuse or nodular), hypo or hyperthyroidism, thyroiditis and neoplasms. Significant information regarding the lesions of thyroid can be obtained by histopatholological examination of the thyroidectomy specimens. Aim:The aim of present study is to determine the prevalence of thyroid lesions in thyroidectomy specimens. Method: About 88 thyroidectomy specimens received in the pathology department between January 2017 to December 2018 were included in the study. The lesions were basically classified into non– neoplastic and neoplastic. Percentages and simple frequency tables were used for data analysis. Result: Out of the 88 thyroidectomy specimens 76 (86.36%) were from females and 12(13.64%) were from males. The female: male ratio was 6.3:1. The age of the patients ranged from 9 to 65 years with a mean age of 37.81 years. 68(77.27%) cases were non–neoplastic and 20(22.72%) cases were neoplastic. The common non–neoplastic lesions were diffuse colloid goiter (32 cases; 47.05%) and multinodular goiter 17(25%). There were 12 benign tumors and 8 malignant tumors. Follicular adenoma was the most common benign tumor (11cases, 91.67%) and Papillary carcinoma was the only malignant tumor (8 cases, 100%). Conclusion: Thyroid diseases showed definite female predominance, with most of them occurring in an age group of 30–39 years. Neoplastic and non– neoplastic disorders affect thyroid gland. Most of the lesions are non– neoplastic. Colloid goiter was the most common non– neoplastic lesion. The most common benign tumor was Follicular adenoma and the most common malignant tumor was papillary carcinoma.