Aims and Objectives: To study clinical and diagnostic profile of pulmonary and extra pulmonary tuberculosis patients in a tertiary care hospital. Material and methods: It was a retrospective study of 100 admitted tuberculosis patients. Clinical symptomatology and diagnostic methods used were retrieved from old hospital records of the enrolled patients. Results: 76% of the patients had fever and cough. Majority (75%) patients had history of weight loss, shortness of breath. 40% patients had extra–pulmonary,37% patients had pulmonary TB, 23% had disseminated TB. Average of hospitalization was 8.6 days. Conclusion: Extra pulmonary TB was the most common cause of hospitalization amongst TB patients. About quarter of patients required rehospitalization which shows the importance of long–term monitoring and follow up in TB patients to prevent fatal complications.