Mucormycosis (phycomycosis, zygomycosis) is a rare opportunistic infection caused by fungi belonging to the Mucorales. It is divided into rhinocerebral, pulmonary, cutaneous, cardiac, gastrointestinal and disseminated, Rhinocerebral form being the most common and most fatal. Mucormycosis is common in immunocompromised individuals and uncontrolled diabetes mellitus is the most common condition. Present study is a prospective study of 10 patients with 6 males and 4 female during period of January 2018 to December 2018. Diabetes mellitus was found in 90% cases and 1 individual was immunocompetent. Histopathology confirmed the diagnosis of mucormycosis. CT scan and MRI were done to assess the extent of disease. Patients were managed with injectable amphotericin B, aggressive surgical debridement and control of underlying condition. Survival rate was 80%. Early diagnosis and treatment is mandatory for a successful management of this infection