IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-4-18796 Original Research Paper PREVALANCE OF HELLP SYNDROME IN PREECLAMPSIA AND ITS FETOMATERNAL OUTCOME IN JHARKHAND INDIA Vijayambade Dr. Prof. Dr. Shashibalasingh Dr. April 2019 8 4 01 02 ABSTRACT

INTRODUCTION: Preeclampsia being a serious challenge in tropical obstetrics. It seriously affects hematological and biochemical changes in body named as HELLP SYNDROM leading to poor feto–maternal outcome. AIM: Prospective interventional study aimed at determining the prevalence of HELLP SYNDROME with respect to COMPLETE AND PARTIAL HELLP SYNDROME in preeclampsia and its fetomaternal outcome. METHOD: One year of prospective study from June 2016 to May 2017 done on patient attending emergency labour room in RIMS, Ranchi, Jharkhand INDIA. 100 Patient with preeclampsia was selected and hematological and biochemical study (CBC, Platelet count, BT, CT, LFT , Sr. LDH, RFT, URIC ACID,PT–INR) was done to know whether patient suffering from HELLP SYNDROME . Maternal outcome studied in terms of maternal age, parity, mode of delivery ,its complication and outcome . Fetal outcome studied with respect to its prematurity, IUGR, IUD, APGAR score.Fisher’s exact test was used for inferential analysis to search for associations among preeclampsia and HELLP Syndrome and its fetomaternal outcome. RESULTS: Study done on 100 preeclamptic patients, 4% complete HELLP syndrome, 14% partial HELLP syndrome. 25% of cases among HELLP syndrome were booked. All patients were elders. 50% of the patient with complete HELLP syndrome were multigravida and 50% were primigravida. Similarly 40% of the patient with partial HELLP syndrome were multigravida and 60% were primigravida. Onset was antepartum in 90% and 10% it was postpartum. Maternal outcome is caesarean section in 40%: uncontrolled hypertension (20%), meconium stain liquor (10%) and fetal distress (5%). In 5% subtotal hysterectomy done because of uncontrolled postpartum haemorrhage, 20% required platelet transfusion. Perinatal outcome was 45% preterm labour, 28% intrauterine death, 67% NICU admission. CONCLUSION :Preeclampsia with severe features and eclampsia is common among the adolescents, unbooked, rural, and low socio–economic group of women in this study.There is need for policy makers to formulate policies toward female education, awareness for ANC check up and provision of social amenities in rural areas.