IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-4-18802 Original Research Paper A STUDY ON PREVALENCE OF SUPERFICIAL MYCOSES IN DIABETIC PATIENTS IN TERTIARY CARE HOSPITAL Dr. April 2019 8 4 01 02 ABSTRACT

INTRODUCTION : Diabetes mellitus ,chronic metabolic dysregulation of glucose is a world wide problem of increasing importance. Cutaneous infection accounts for 20–50% of the skin manifestation among diabetic patients due to poor glycaemic control[1,2,3,4]. The fungal infections is the commonest cutaneous infection in diabetic patients.Moreover the prevalence of superficial mycoses namely onychomycosis and tinea pedis is 75% in diabetic patients especially in type 2.[5,6,7].The relative occurrence of the etiological agents of these superficial mycotic infections varies among countries[8]. Hence this study was conducted to know the prevalence and the causative agents in our region. . This causes considerable morbidity,disability and also leading cause for foot amputations [9]and hospital stay.[10,11,12]. Hence early detection of superficial mycoses especially tinea pedis and onychomycosis of toe nails , adequate dosage of antifungal agents with good glycaemic control can save the limb. Aims & Objectives:To isolate and identify the casautive organisms of superficial mycoses in diabetic patients. To study the prevalence of superficial mycoses in diabetes mellitus. Materials and methods: A cross sectional study was conducted with 150 diabetic patients with superficial mycotic infection by collecting skin scrapings and nail clippings.Direct microscopy with KOH mount followed by inoculation onto SDA in duplicate set was done to be incubated at 250C and 370C.Sample was also inoculated onto DTM with antibiotics and chlorhexidine and incubated at 250C. Results: Out of 150 clinically suspected cases,skin scrappings were collected from 63 patients and nail clippings 87.Among these KOH positivity was seen in 65 samples but culture positivity was 73 samples.The predominant pathogens isolated from skin and nail were dermatophytes 33(84%),Trichophyton mentagrophytes followed by Trichophyton rubrum and among candida species,candida tropicalis .Non dermatophytic moulds 9(26%)(Rhizopus sp.4,Fusarium sp.2,Aspergillus fumigates 2 and Aspergillus 1) were isolated from nail clippings.