IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-4-18866 Original Research Paper COMPARISION OF BOLUS PHENYLEPHRINE AND EPHEDRINE FOR MAINTAINING OF BLOOD PRESSURE DURING SPINAL ANAESTHESIA IN LOWER UTERINE CAESAREAN SECTION. MUDIGANTI Dr. Dr.R.Pratap Dr. April 2019 8 4 01 02 ABSTRACT

It is more than 125 years since spinal anaesthesia was first used in a surgical procedure . During this period a lot has been learnt except for the fact that it is a simple technique with little sophistication. Today anesthesiologists throughout the world use it successfully for performing various surgeries specifically cesarean deliveries and those involving lower abdomen, urological and lower limbs as well. One of the controversial issues related with use of spinal anaesthesia is its hypotensive effect which is widely studied in cesarean procedures owing to the compounding effect of aortocaval compression and peripheral vasodilatation leading to decrease in cardiac output1,2,3. Even in non–obstetric surgeries incidence of hypotension has been reported to be around 33%1,2. The incidence of hypotension depends on the desired block height, age of patient, location of spinal puncture site and baseline systolic blood pressure. No doubt hypotension during spinal anaesthesia is a frequent occurrence in lower uterine cesarean section and despite numerous attempts to try drugs which could restrict this incidence it continues to be cause of concern for an anesthetist. Use of some adjuvant drugs such as Phenylephrine and Ephedrine is quite common in order to tackle the problem of hypotension in LSCS under spinal anaesthesia. These drugs have been shown to vary in their efficacy depending on the route of administration, dosage and protocol in which they are used. Considering the high incidence of hypotension during LSCS under spinal anaesthesia, a preemptive approach is recommended by some researchers4,5. However some other researchers are of the view that a preemptive vasopressor might affect the rostral spread of spinal anaesthesia, hence bolus maintenance is recommended by some other workers as and when hypotensive events take place. Although the three drugs are being used effectively with minor differences in their performance however, most of the literature on this issue generally addresses their use in cesarean section6.