Background: Patellofemoral osteoarthritis is common clinical problem seen in all age group and presented in general practice. Knee pain may caused by an injury such as ruptured ligament or torn cartilage, gout, rheumatoid arthritis, chondromalacia, tibiofemoral osteoarthritis and patellofemoral osteoarthritis. Globally it is estimated that among all the knee pain patients 12% of patients suffer by patellofemoral osteoarthritis. The incidence of symptomatic patellofemoral osteoarthritis of the knee is more common in people more than 55 years of age. Disease of patellofemoral joint can cause severe pain particularly when the patient is ascending and descending stairs, cycling, sitting with knee flexed for prolonged period of time, squatting and kneeling. The study aims to find and compare the effects of patellar taping and mulligan’s mobilization with movement techniques on pain and knee function among patellofemoral osteoarthritis patients. Methods: Twenty clinically diagnosed patellofemoral osteoarthritis patients were selected for the study and randomly divided in to two groups A and B. Group A received patellar taping and group B received mulligan’s mobilization with movement techniques. Intervention lasted for one week. Knee pain and knee function were assessed by visual analog scale and the western ontario and mcmaster universities osteoarthritis index (WOMAC index) respectively. Conclusion: Both patellar taping and mulligan’s mobilization with movement techniques were effective in reducing knee pain and improving knee function among patellofemoral osteoarthritis patients. When comparing both patellar taping is more effective than mulligan’s mobilization with movement techniques in reducing knee pain and improving knee function among patellofemoral osteoarthritis patients