Background: Gall stones are among the most common causes of gastrointestinal illness requiring hospitalisation. Indeed operations on billiary tract are among the most common abdominal procedure performed in the United States, with more than 6,00,000 cholecystectomies performed annually. Laparoscopic cholecystectomy which is the gold standard for the treatment of gall stone disease today. we have made an attempt to evaluate the efficacy and effectiveness of single incision laparoscopic cholecystectomy compared to the gold standard multiport laparoscopic cholecystectomy. Conclusion: postoperative mortality , morbidity & complications were minimal & same in both groups yet the time taken for surgery ,significance conversion rate , technical difficulties & incidence of portsite infection was higher in single incision laparoscopic cholecystectomy as compared to conventional laparoscopic cholecystectomy.