IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-4-19075 Original Research Paper Relationship Between The Ejection Fraction In Echocardiography With Liver Function In Heart Failure Patients Hayati Lubis Dr. Zainal Safri Dr. April 2019 8 4 01 02 ABSTRACT

Background: Heart failure (HF) is a complex clinical syndrome, which is based on the inability of the heart to pump blood throughout the body adequately, due to structural and functional disorders of the heart. The most common cause of left ventricular myocardial dysfunction. Heart failure is described by the measurement of left ventricular (LV) ejection fraction (LV). Heart failure with decreased ejection fraction (HFrEF) is characterized by LVEF ≤40%; preserved EF (HFpEF) is characterized by LVEF ≥50% assessed by dopplerococardiography. In heart failure, the heart cannot supply oxygen adequately, so it can cause damage to other organ systems, such as the liver. It is important to identify from the outset of liver biochemical abnormalities in patients with heart failure, because the examination is useful in assessing the severity and duration of heart failure. Aim:To determine the relationship between ejection fraction on echocardiography and liver function in heart failure patients. Method: This cross–sectional study was conducted at the H. Adam Malik General Hospital in Medan in June 2017 until the research sample was fulfilled. Heart failure patients performed echocardiography and blood tests: SGOT, SGPT, Bilirubin, ALP, GGT, Albumin. Data analysis (Chi–square / fisher exact test) using SPSS. Result: Subjects were male 36 patients (69.2%), and women 16 patients (30.8%), with an average age of 52.08 ± 10.52 years. The frequency of increasing total bilirubin and GGT is greater than for other liver functions. Liver function characteristics of SGOT, SGPT, total bilirubin, ALP, and GGT had a higher mean of ejection fraction <= 40% compared to ejection fraction> 40%. With the analysis of the Fisher Exact test p value <0.05 for the relationship of Ejection Fraction to total bilirubin (p = 0.001) and GGT (p = 0.016). Conclusion: There is a relationship between ejection fraction and liver function and what is meaningful is total bilirubin with GGT.