Hodgkin’s lymphoma Comprise approximately 20–30% of all malignant lymphoma. It has bimodal age distribution. IHC markers CD30 and CD15 are key markers to typify the Hodgkin’s lymphoma. In the present study our aim is to study the role of IHC markers in Hodgkin’s lymphoma. 200 cases of Hodgkin’s lymphoma were recruited during August 2015 to April 2017 and differentiated in to subtypes basing upon histopathological features and immunohistochemistry. Classical Hodgkin’s lymphoma was found to be the common type, mixed cellularity subtype was found to be the most common subtype among classical Hodgkin’s lymphoma. CD15 and CD30 was found in almost all classical Hodgkin’s lymphoma. CD30 was more specific for Hodgkin’s lymphoma. Our study indicates that IHC has key role to diagnose Hodgkin’s lymphoma