Introduction: Gastric cancer is a heterogeneous disease that demands continued attention and research with regard to prevention, early detection and novel therapeutic options. Candida infection can occur in patients with cancer and cancer related therapy such as chemotherapy, radiotherapy. We have tried to study the endoscopy and histological features of Gastric carcinoma lesions associated with Candidiasis. Materials and Methods: Gastric biopsy specimens of 34 gastric carcinoma patients were processed for Histopathological examination (HPE) using Hematoxylin and eosin (H&E) staining and Periodic Acid Schiff (PAS) stain. Results: Majority of the gastric carcinoma patients were observed above the age of 61 years, i.e., 24 (70.5%) out of 34 total cases. Most common type was intestinal, 24 (70.5%) out of 34 gastric carcinoma patients followed by diffuse (20.5%) and unclassified (8.8%). Out of 34 gastric carcinoma cases, 6 (17.6%) patients had candidiasis. Conclusion: Better way to avoid fungal infections is early recognition; early detection of fungus can help to prevent serious illness. Microbial infection and cancer risk still have to evaluate with evidence based researches