The GLOBOCAN Cancer project 2012 predicted that the incidence of cancer in India is likely to double in the next two decades and reach approximately 1.7 million new cases by 2035 3 . In Delhi, as per the GATS 2 report, the usage was (17.8%) and in Haryana (23.6%). 2 This has not changed much as the GATS–2010 report showed that more than one–third (35%) of adults in India used tobacco in one form or the other. Further, most of these new cancers are related to tobacco use in rural areas and surveillance activities in these areas are poorly organized to pre–empt the early diagnosis these oral cancers. Owing to the high prevalence of Oral Cancer in Haryana and lack of screening, we organized opportunistic screening and visual screening for smokers and smokeless tobacco patients (SLT) (using gutka, pan, khaini with tobacco) in two rural areas of Haryana namely Panipat and Jhajjar, in Haryana. This study was aimed to carry out opportunistic screening of tobacco users in two tertiary care hospitals in the Department of TB and Chest and Department of Dentistry. Deaddiction and follow–up with e–mobile technology was carried out in the Department of TB and Chest, in Panipat, Haryana, India. Based on the patterns of lesions observed during visual inspection of these patients, oral spot plates (OSPs) were developed which were subsequently used to induce a behavior change in these patients. Patients who showed a positive behavior change were referred to the deaddiction OPD of the Department of TB and Chest. The study methodology adopted in this research model is longitudinal where patients having suspected lesions would be followed up with deaddiction medications and monitored with e–mobile technology. The study would also analyze the potential role of opportunistic screening and proactive screening in the prevention of smokers and smokeless tobacco (SLT) related cancer