IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-5-19353 Original Research Paper MICROALBUMINURIA AND ITS ASSOCIATION WITH RENAL FUNCTION AND SERUM URIC ACID LEVEL IN PREHYPERTENSION Godara Dr. Dr. Maheep Sinha Dr. May 2019 8 5 01 02 ABSTRACT

Microalbuminuria (MA) develops from progressive, subclinical, structural and functional changes within the kidney and represents a sensitive marker of early renal disease. Therefore, this study planned to explore the association of MA with renal variables in patients of prehypertension. For the study, 100 patients with prehypertension visiting the Medicine out–patient department of Mahatma Gandhi Medical College and Hospital, Jaipur were selected based on the predefined inclusion and exclusion criteria. Of total prehypertensive patients 32% exhibited MA. On comparing the renal profile it was observed that S. Urea, Creatinine and Uric acid were significantly higher in the microalbuminuric group. (P=0.000, P=0.004, P=0.002) respectively. On applying Pearson’s correlation, the present study reported a significant association between S. uric acid & AC and between uric acid and urinary albumin. Findings of the present study suggest that microalbuminuria may be an independent risk factor in prehypertension. Increased prevalence of microalbuminuria and its significant correlation with renal function test indicates significant association between prehypertension and renal dysfunction.