Road traffic accidents which is the leading cause for compound fracture cases and a growing problem worldwide. In developing countries like India, the topic is of great importance since most of the cases of these fractures end up in fracture site infection because of many risk factors like gross contamination, delayed intervention etc. One fifty six swabs/ pus specimens from various compound fracture sites suspected to be infected were collected during July 2017 to May 2018 and processed, by standard methods. Antibiotic susceptibility testing of all the isolates was done. 64% of patients developed infection at the fracture site. Klebsiella species was the commonest organism isolated 30% followed by others . Unlike previous studies, Klebsiella constituted majority of the cases instead of Staphylococcus. There is an urgent need to adopt basic principles of asepsis and sterilisation and to make judicious use antibiotics.