INTRODUCTION: Leprosy is a chronic granulomatous disease of the peripheral nerves, mucosa of the upper respiratory tract and skin. Due to its clinical diversity as well as its ability to mimic other diseases, makes histopathological examination a helpful diagnostic tool to confirm the diagnosis. METHOD AND MATERIAL: A prospective study was conducted in a tertiary care teaching institute in Jammu. In this study, all newly diagnosed untreated patients were enrolled over a period of one year. RESULTS: A total of 56 cases of leprosy were studied over a duration of one year. Patients of both sexes were affected with predominance of males. Preponderance of leprosy was seen in the age group of 21–30 years. Both clinically and histopathologically, BT constituted the predominant group. Maximum clinico–histopathological concordance was prominent in indeterminate leprosy. CONCLUSION: Histopathological examination of skin lesions is gold standard for precise diagnosis and typing of leprosy.