Oral cavity and Oropharyngeal squamous cell carcinoma accounts for more than 40% cancers in India. Exfoliative cytology by using scrape method has been shown to be an efficient diagnostic method, particularly in the more advanced stages of the disease. This study was done to correlate the findings of scrape cytology & histopathology and to evaluate the utility of scrape cytology for rapid & routine diagnosis of malignancy Ninety four patients with suspected oral cavity or oropharyngeal carcinoma were included in the study. Scrape sample was stained using Papanicolaous method and the histological sections were stained with hematoxylin and eosin. Diagnostic validity of Scrape cytology was compared with histopathology and was expressed in terms of sensitivity, specificity, positive predictive value and negative predictive value. It was seen that even though scrape cytology is used for identifying atypical cells and has almost comparable diagnostic validity with histopathological examination, it cannot be substituted for the same owing to its decreased sensitivity