IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-6-19635 Original Research Paper Evaluation of neonatal seizuires with etiological factors and immediate outcome Zende Dr. June 2019 8 6 01 02 ABSTRACT

Introduction: The developing brain has an increased susceptibility to seizure activity and neonatal seizures can adversely affect neurodevelopment outcome. In newborn infant, seizures are always due to an underlying, cerebral or biochemical abnormality. Seizures are associated with poor neurodevelopmental outcome if not diagnosed early and treated properly. So the purpose of the study was to evaluate the risk factors of seizures in low birth weight babies and evaluate the immediate clinical outcome. Materials And Methods: A total of 100 low birth weight neonatal babies, admitted to Neonatal Unit from Feb 2015 to July 2016,Fifty low birth weight babies with neonatal seizures served as cases while, another 50 low birth weight babies matched for gestation and sex, not having seizures, served as controls. Observations: Most common type of seizures observed were subtle (20) while myoclonic seizures (1) were least common.Neurological outcome was better with tonic generalized type (01.96%) and worst with clonic focal type (13.04%).Mortality was highest with tonic focal (48.57%) and lowest with subtle seizures. Conclusion: Seizures are associated with poor neurodevelopmental outcome if not diagnosed early and treated properly