IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-6-19685 Original Research Paper A COMPARATIVE STUDY OF CAUDAL BLOCK WITH BUPIVACAINE AND BUPIVACAINE WITH CLONIDINE IN INFRAUMBILICAL SURGERIES IN CHILDREN Choudhary Dr. Manish Singh Chauhan Dr. June 2019 8 6 01 02 ABSTRACT

Introduction:– Pain management is an essential component of care provided by paediatric anaesthesiologists. The use of regional anaesthetic techniques in infants and children has become increasingly accepted as standard of care during final decades of twentieth century. Caudal analgesia is one of the most popular regional anaesthetic technique employed in paediatric surgery for lower abdominal, urological, and lower limb operations. Single dose caudal analgesia with bupivacaine is very safe and has been effectively used in pediatric surgical procedures for provision of postoperative analgesia. Nowadays clonidine, an alpha 2 agonist has been extensively used in neuraxial blocks and peripheral nerve blocks to prolong the action of bupivacaine. It is one of the most commonly used additives with bupivacaine for caudal analgesia in children. So this clinical study is planned to compare caudal bupivacaine with clonidine and bupivacaine alone with regards to hemodynamic changes, analgesic potency and side effects in children. Material and methods:– This study was conducted at Govt Medical College and Associate group of Hospitals, Kota from jan.2018 to dec.2018. This study included 60 children, of either sex, coming for various elective infra–umbilical surgical procedures. Standard procedure was followed for caudal block. The patients were randomly divided into 2 groups of 30 each. Group B received 0.25% of bupivacaine 1 ml/kg. Group BC received 0.25% of bupivacaine 1 ml/kg with clonidine 1.0µg/kg. All data were collected and analysed with the help of suitable statistical parameters. Results:– The mean duration of analgesia was 250.33 ± 41.4 min in group B with a range of 180 to 355 min. In group BC, the mean duration of analgesia was 433.5 ± 60.2 min with a range of 265 to 530 min. The difference in the mean duration of analgesia was statistically highly significant (p<0.001).