Introduction: Cirrhosis of liver has multifactorial etiology Himsworth described cirrhosis of the liver as "Diffuse hepatic fibrosis and post necrotic scarring of the liver as "Diffuse hepatic fibrosis and post necrotic scarring with nodular hyperplasia". These have some relation to etiology, pathology and prognosis of cirrhosis of liver. Cirrhosis is defined anatomically as a diffuse process with fibrosis and nodular regeneration which follows hepatocellular necrosis. Although causes are many the end result is same (Anthony et al 1977). Cirrhosis of liver is said to be an irreversible condition but the process can be arrested, if the etiological factors are eliminated in many of the cases. Material and Methods: The study was conducted on those patients who were admitted to in–patient Medical Wards of L.L.R. and Associated Hospials, Kanpur and presented clinically as well as biochemically as cirrhosis of liver. The patients were picked up from both pediatric as well as adult groups and from both sexes. Result & Discussion :The present study showed that cirrhosis of liver is common problem in Kanpur. 61 patients were admitted in the Medical Wards of L.L.R. and Associated Hospitals, Kanpur, during period of one year from August 1989 to July 1990. The incidence of alcoholic cirrhosis was 18.03% i.e. only amonqQgst 11 patients. The remaining 50 patients were of non–alcoholic cirrhosis (81.97%). In the present study, 62% patients were in the age group 31 to 50 years with the mean age of 35.5 years. These were no patients in between the age of 3 to 10 years.