Background: Single small enhancing computed tomography lesions may occur in several infections and neoplastic diseases of central nervous system and are most common radiological abnormality seen in patients with focal seizure in India. Aim of this study was to access the clinical and radiological spectrum of small ring enhancing lesions on CT scan head in patients of Jammu Region. Material and Methods: A total of 100 patients with small ring enhancing CT lesion /lesions presented to neurology and neurosurgery OPD of a tertiary health care center of Jammu region were prospectively enrolled in this study. Detail history, general physical examination, detail neurological examination and investigations like CBC, ESR, Mantoux test, cysticercus serology were done for all patients. Among the patients of neurocysticercosis (NCC) who had single lesion were labelled as group 1 and who had multiple lesions were labelled as group II. Patients having single lesion were divided into two sub groups 1a and 1b. Patients in group 1a and group II were subjected to Albendazole therapy and anti convulsants, whereas group 1b patients receive only anti convulsant therapy. All these patients were kept under follow up on OPD basis and assessed by CT head after 03 months. Results: Out of 100 patients enrolled, 58 were male and 48 female. Age of patients ranges from 03 to 65 years with mean age of 28.8years. Most common presentation was focal seizure in 50% patients followed by generalized seizure in 35%. On CT scan most common diagnosis of neurocysticercosis was made in 80% patients, tuberculoma in 10%, glioma in 5%, pyogenic abscess in 4%, and AV malformation in 1% patients. Coalescing lesion in 5% and non–coalescing lesions in 95%, solitary lesions in 56% and multiple in 44%. Lesions with thin wall was seen on CT in 82%, thick wall in 13%, irregular wall in 5% and calcification in 2% patients. Overall improvement was seen in 10 patients in group 1a, 9 patients in group 1b and 12 (33.33%) patients in group II. The difference in group 1a and group 1b was not found to statistically significant, chi square= 0.09 (P=0.76%) Conclusions: Most common small ring enhancing lesion on CT scan was neurocysticercosis in 80% patients followed by tuberculoma in 10%, glioma in 5%, pyogenic abscess in 4%, and AV malformation 1% patient in this study. Overall improvement was seen in 10 patients in group 1a, 9 patients in group 1b and 12 (33.33%) patients in group II. The difference in group 1a and group 1b was not found to statistically significant, chi square= 0.09 (P=0.76%)