A prospective, observer blinded comparative study was done on 60 nulliparous women at >37 weeks of gestation and 18–35 years age group, requested for epidural labor analgesia, In Group BS Sufentanil 12.5 mcg (0.25 ml) + 2.5 ml Bupivacaine (0.5%) + 7.25 ml normal saline was given and in Group BF Fentanyl 25mcg (0.5 ml) + 2.5 ml Bupivacaine (0.5%) + 7 ml normal saline given.It was observed that epidural Fentanyl and Sufentanil with low dosage of Bupivacaine improved the quality of analgesia in early labour in both the groups. There were no significant adverse effects like maternal hypotension, sedation, respiratory depression, nausea/ vomiting, pruritus, shivering in both the groups. Instrumental delivery did not increase and maternal satisfaction was excellent. Neonatal Apgar score in one and five minutes in both the groups was also 9–10. Regarding the cost and availability of both the drugs fentanyl may be the better choice in epidural labor analgesia