Background: Obstructive uropathy is a common clinical problem and results from structural impedance to urine flow anywhere along the urinary tract. It may lead to irreversible renal damage if not timely treated and so proper evaluation and accurate diagnosis is necessary for timely intervention and management Aim/Objectives: To assess the role of Multidetector Ccomputed Tomography (MDCT) urography in patients presenting with obstructive uropathy Material and Methods: Sixty consecutive patients with clinical and sonographic manifestations of ureteral obstruction were included in the study. Detailed history and findings of clinical examination were recorded. Non contrast, contrast enhanced and urographic phase images were obtained. Positive findings were recorded in detail and tabulated. Side, site and cause of urinary obstruction were noted based on MDCT urography findings. Results: Unilateral urinary obstruction was seen in 53 patients (88.3%) while 7 patients (11.7%) had bilateral urinary obstruction. The commonest cause of urinary obstruction was urinary tract calculi seen in 41 patients (68.3%). Vesical masses were causes of unilateral obstruction in 7 patients and bilateral obstruction in 1 patient. Less common causes included Pelvi–Ureteric Junction (PUJ) obstruction, ureteric stricture, ureteric masses and extrinsic compression of ureter by abdominal masses/enlarged lymph nodes. Solitary case each of circumcaval ureter, vesico–vaginal fistula and bladder neck obstruction were also seen. Conclusions: MDCT urography allows rapid detection of level and cause of urinary tract obstruction and thus significantly aids in the timely and effective management.