IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-7-19836 Original Research Paper PAEDIATRIC UTI: POINTS OF CONCERN: A CLINICOBACTERIOLOGICAL ANALYSIS IN A TERTIARY CARE HOSPITAL Purba Mukherjee Dr. Dr. Sudeb Roy Dr. July 2019 8 7 01 02 ABSTRACT

 

Paediatric UTI is a matter of grave concern particularly at less than two years of age due to predisposition to serious future complications and limited treatment options resulting from ever–increasing antibiotic resistance. This study included 392 established cases of paediatric UTI. Gram negative bacteria were isolated in 68.9% cases, predominated by Escherichia coli (34.7%). It was followed by Klebsiella species (27.3%), Enterococcus faecalis (12.2%), Acinetobacter species (7.4%), Pseudomonas aeruginosa (4.3%), and other GNB. Staphylococcus saprophyticus (4.1%) and Staphylococcus aureus (3.1%) were less common. Antibiograms of the isolates showed very low sensitivity to all commonly prescribed antibiotics, namely, ampicillin, amoxyclav, ceftriaxone, cefotaxime, gentamicin, cotrimoxazole, nitrofurantoin, ciprofloxacin and levofloxacin– making them practically irrational to choose. Most of the GNB were susceptible to imipenem, whereas, gram positive cocci were uniformly susceptible to vancomycin and linezolid.