Parkinson disease (PD) is the second most common neurodegenerative disorder that causes progressive motor and non–motor disability. This condition is diagnosed clinically and is characterized by the presence of bradykinesia, accompanied either by rest tremor or rigidity. The present study aimed to provide the demographic and clinical profile of PD in patients from Hyderabad and also to create a database on PD in this region. Methods: A prospective cross–sectional hospital based study was conducted over a period of 3 years commencing in December 2014. The study included cases of PD diagnosed in accordance with the United Kingdom PD Society Brain Bank criteria and analyzed its demographic and clinical features. Results: 40 patients (26 males, 14 females) were found to have features compatible with PD. The average age at onset was 51.55± 10.18 years. Majority of patients had onset of PD at an older age (≥50 years; 24 patients, 60%) when compared to the rest who were younger (age<50 years, 16 patients, 40%).The most common initial symptom was tremor (36 patients, 90 %). Postural instability was observed in 22% patients. The average progression from mild to moderate/severe PD (stage3) was seen to be 3.8±5 years among the young and 3.7±3.2 years among the older patients. Non motor feature of PD was observed in 25% patients and the most common non motor feature was found to be disturbance in sleep (15%) Conclusion; Unilateral limb tremor was seen to be the most common initial symptom and disturbance in sleep was the most common non motor symptom. Male predominance and older onset of PD was observed in this region.