Pleural effusion is one of the commonest problems with which patients present to the hospital. Many studies have reported that in relatively large numbers of patients with pleural effusion,definite diagnosis could not be made, despite extensive investigations.Bronchoscopy has low diagnostic yield in pleural effusion, unless the pleural effusion is secondary to an obstructing lesion in the airway or patient has associated haemoptysis, or effusion is associated with parenchymal radiographic abnormality. This observational prospective study was carried out in 22 patients recruited over 18 months duration at a tertiary care centre. Out of 22 patients, 8 patients were having neoplastic endobronchial growth and one patient was diagnosed to have Aspergillosis in Bronchoscopic biopsy and presented as Endobronchial growth.So the Diagnostic yield of bronchoscopy in this study was 40.9%.