Background: Providing safe and quality health care while optimizing resources at a reasonable cost has been firmly established as a significant challenge. In order to overcome these challenges, health care organizations need to continuously upgrade and adopt Disruptive Innovative Practices. Materials and Methodology: A semi–structured questionnaire was given to all Clinicians and Hospital Administrators which had four segments namely Demographic profile, Awareness, Acceptability and Perceived benefits of Innovative Practices. The significance of association between Innovative Practices and awareness and its acceptability because of perceived benefits was established using SPSS ver 20. Results: The response rate was 88.33%. The overall Awareness was good for ICT and Robotic surgeries whereas Acceptability was good for ICT and Cloud computing which reiterates the fact that people prefer to focus on what is important to them in the present scenario. Conclusion: If an organization does not optimally use the current resources, or forgoes investment in technology, it may perform below an idealized potential. Implications: This study provides foresight information about obtaining information regarding end–user acceptability before investing in Disruptive Innovative Practices thereby maximizing the chances of successful integration of technology with the organizational requirements. Level of evidence: By paying attention to these new technologies we can better inform the development of adoption techniques by identifying those Innovative Practices which are acceptable.