Objective: The present study is aimed to determine the distribution pattern of the ABO and Rh blood groups among first MBBS female students in medical college Jabalpur. Materials and Methods: We have selected 57 first MBBS female medical students of known blood group and compared it with previous studies. Observations & Results: O+ve 18, B+ve 19, B–ve 04, A+ve 10, A– ve 02, AB+ve 04 Conclusion: Present study shows that the most common blood group among first MBBS female medical students at NSCB medical college Jabalpur is ‘B’ blood group followed by ‘O’ blood group and least common blood group is ‘AB’ blood group.