Introduction : In the present era of target imaging for foetal anomalies (TIFFA), more and more cases of congenital anomalies were detected at the early gestational age and terminated medically. Foetal autopsy will help to ascertain the imaging findings and to find out the cause of intrauterine foetal death. Aims & objectives: To analyse various congenital anomalies detected during foetal autopsy in correlation with antenatal imaging findings and to identify cause of intrauterine death during second and third trimester of pregnancy. Materials and Methods: Foetal autopsies were performed as per standard protocol on all foetuses received in the Department of Pathology over a period of 5 years from June 2013 to June 2018. Results: Total of 54 foetal autopsies from 52 mothers were performed over a period of five years. Of the 54 cases, the predominant cause of foetal loss were found to be due to MTP following congenital anomalies in 34 cases (65.3 %) and one case (1.9%) of SLE on methotrexate, followed by intrauterine deaths due to uteroplacental insufficiency in 17 cases (32.7%), and twins complicating pregnancy in 3 cases ( 5.7% ). Among the 34 congenital anomalies, central nervous system defects were seen in 9 cases (26.4%) followed by musculoskeletal defects in 8 cases (23.5%), cardiac vascular anomalies in 7 cases (20.5%), foetal hydrops in 3 cases (8.8%) and congenital syndromes in 3 cases (8.8%). Conclusion: The organized post–mortem examination of the foetus is superior in identifying the cause of death along with appropriate antenatal history and radiological findings.