IJSR International Journal of Scientific Research 2277 - 8179 Indian Society for Health and Advanced Research ijsr-8-8-20162 Original Research Paper Nasal carriage rate of potential pathogens among healthy population Veera Lavanya Dr. Sanjay Pratap Singh Dr. Arjit Sen Dr. August 2019 8 8 01 02 ABSTRACT

Introduction: Nasal cavity can act as filter of unwanted particles entering the body & also has potential to cause endogenous infection by harbouring potential pathogens. Many studies have been done in hospital set up assessing nasal carriage, but only few studies are available on healthy adults in community . This study aims to know the prevalence of nasal carriers with potential pathogens in the community. Material & Methods: 100 Nasal swabs were taken aseptically from the anterior nares of, healthy people from the community & processed in the lab for potential pathogens. Results: All 100 participants have shown some growth. 86% of the samples grew Coagulase Negative Staphylococcus (CONS) , predominantly S.epidermidis. Total of 54.0% were colonized with at least one of the known potential bacterial pathogens assessed. The overall prevalence of nasal S. aureus carriage was 30.0% ; amongst them 11 (36.6%) were MRSA. 34 % of the participants were nasally colonized with Enterobacteriaceae (Escherichia coli (9.0 %), Proteus mirabilis (4.0%), Citrobacter koseri (8.0 %), Enterobacter aerogenes (7.0 %), Klebsiella pneumoniae (8.0 %), Morganella morganii (1 %)) and 3 % with non–fermenters Acinetobacter baumannii (1.0%), Pseudomonas sps (2 %). Conclusion: Significant variation in nasal microbiota and differences in their composition between S. aureus carriers and noncarriers was observed. Cocolonisation rates with other organisms were less in MRSA carriers when compared to S.aureus carriers. MRSA carrier rate was higher in this study, as our study population was from male gender which is correlating with other studies. Epidemiological studies with genotyping are required to understand this in detail