Introduction: Success of Thrombolytic therapy depends on timely initiation of it. Acute Ischemic stroke patients have facing challenges in seeking medical care as there is a common delay in most of the patient‘s admission. Methods: A prospective study was conducted in INDIANA Hospital and Heart Institute, Mangalore, Karnataka to assess the hurdles in admission of acute ischemic stroke patients, who got admitted in emergency department with acute ischemic stroke and arrived within 72 hours. A standard questionnaire was provided to the patients and their attendant to rule out the cause of delay. Results: The median time of patients who have arrived at the emergency department was of 10 hours in which 25 percent were arrived within 6 hours and the 58 percent were arrived within 10 hours and the rest 17 percent were arrived more than 10 hours of onset of symptoms. Conclusion: The most common cause of delay was identification of stroke symptoms, time of occurrence of stroke, transport delay and admission of patients in non–stroke centers. Required measures to be taken to educate people about identification of stroke symptoms and importance of Golden hours in admission of patients to improve stroke outcomes