Aim :of the present study is to know the importance of PBL that is taught in different parts of world & comparing that with of present study. Place of the Study:In the class room of Lincoln University College, Malaysian Airlines Campus, Kelana jaya, Petaling jaya Malaysia. Period of Study:This study was done during the year 2016–2017 for second year MD students Materials&Methods:Forty students from second year MD were divided into 5 groups comprising 8 students in each group. They were given two problems one after another in the span of two months They were advised to examine two cases with discussion of lab investigations followed BY differential diagnosis of each cases. Then were advised to do references from Harisson,Davidson & other International books. A male child aged 3–4 years with history of bleeding through nose & an elderly person aged 61 years with history of chest pain constituted the materials for the present study. In each case, proper antenatal history of mother like drug history taken in first trimester of pregnancy, past history marriage history to rule out consanguineous from non–consanguineous marriage any history of systemic diseases, treatment taken in the past any history similar complaints should be noted down. Differential diagnosed were advised to narrate by the students on rotation .Later every student was told to present both cases one by one on rotation. Any mistakes told by the students were rectified In the second round of PBL meeting ,Differential diagnosis was made to tell by the students to rule out one by one and Final Diagnosis was made. Later its clinical importance was discussed. CONCLUSION; study helped students to solve the two problems clearly, –epistaxis & myocardial infarction very clearly through PROBLEM BASED LEARNING which involved small group discussion and essential skills .