Introduction: Surgical resection has been the gold standard for localized esophageal cancer for decades. The application of minimally invasive surgery has been explored and found to be feasible in the management of esophageal cancer, although concern has been expressed about its safety, efficacy, oncologic value. ] This study discusses MIE indications, techniques, and outcomes in the management of esophageal cancer. Methodology: The data was collected retrospectively, for nonrandomized analytical study. Patients operated from July 2013 to March 2016 in Gujarat Cancer and Research Institute, Ahmedabad, MIE was performed in 23 patients of carcinoma of esophagus for open group, 24 cases of esophageal cancer were selected. Results: The average duration of surgery observed in MIE group was 4.2 hours where as in open esophagectomy group was 5 hours. The average blood loss during MIE surgery was 255 ml whereas during open esophagectomy was 385 ml. Post operative morbidity and mortality is also comparable between both groups. Conclusion: The implementation of MIE seems inevitable inspite of absence of randomized controlled trials as it has the potential to improve morbidity, decrease blood loss and reduce hospital stay. Overall, MIE is an integral tool that is safe and effective in the surgical management of esophageal cancer