Background: The aim of this study is to determine the prevalence of Gastroesophageal reflux (GER) in patients with recurrent and/or persistent lower respiratory tract illness (R/P–LRTI) and thus to possibly predict this subgroup of patients in whom Gastroesophageal reflux disease (GERD) may be an underline aggravating factor, removal of which may help in amelioration of symptom. Methods: This was cross sectional study carried out in a tertiary care hospital in a western Maharashtra. Total of one hundred and twenty infants and young children from 6 months to 2 years of age attending OPD’s, Emergency ward and Clinics in Department of Paediatrics, with pre–decided inclusion and exclusion criteria were included in the study. Those patients with I–GERQ GERD score more than or equal to 5 were further evaluated with Barium Swallow and Upper GI scopy and esophageal biopsy. Statistical analysis was done computer aided using SPSS 20. Association between two variables were studied using chi–square test & comparison between two continuous variables was done using unpaired t test. P value <0.05 was considered significant. Results: Out of 120 cases studied 42 were observed with I–GERQ score greater than 5 which were then investigated and 31 were confirmed with positive GERD and observed prevalence of GERD was 25.83%. Out of 31 children of GERD male were predominant than female. Overall GER was higher in Recurrent Pneumonia, Reactive Airway Disease and Persistent Pneumonia. Most common symptoms observed in children were breathing problems (119 Cases, 99.17%) and regurgitation (105 cases, 87.50%). Conclusions: Observed prevalence of GERD was 25.83%. GER was more common in Recurrent Pneumonia at different sites, Reactive Airway Disease and Persistent Pneumonia. Endoscopy with biopsy is useful in detecting most of the reflux esophagitis.