Context: The accurate determination of vertical jaw relation is extremely important for successfully achieving comfort, function and esthetics for an edentulous patient. Aim: The aim of this study was to find a correlation between vertical dimension of occlusion (VDO) and length of right hand palm. Methods and Material: The study was conducted on 60 dentate subjects (30 Males and 30 Females) who fulfilled the inclusion criteria. Anthropometric measurements of vertical dimension of occlusion and length of right hand palm were recorded. Correlation between VDO and length of right hand palm was studied using Pearson’s correlation test and unpaired t test used to find correlation among males and females VDO & right palm. Results: Pearson’s correlation test showed that VDO in both males (r=0.8001, p value=000) and females (r= 0.9556, p value=000) has strong coefficient correlation with the length of right hand palm. The study also suggested by unpaired t test that there is no statistical correlation between the males and females VDO (t= –0.3366, p value=0.7377) and length of right palm (t= –0.1046, p value=0.9170) Conclusions: Within the limitations of this study, it was concluded that for males and female subjects VDO and length of right hand palm was highly correlated and this anthropometric measurement can be used to determine VDO in edentulous patient.